NTA provides a curated pipeline of vetted opportunities aligned with industry and national priorities. We are continuously consolidating new opportunities from Catalyst Partners, government requirements, and industry targets. Contact us to share your opportunities with NTA’s diverse community or organizations. Join NTA today to receive email notifications.
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Draft SOO: Operationalizing Novel Technologies for Advanced Rapid Generation of Effective MCMs
Anticipated Release Date: Q4FY23 The Joint Science and Technology Office (JSTO) within the Defense Threat Reduction Agency (DTRA) is seeking …
Sailor Post-Traumatic Stress Disorder (PTSD) Risk Prediction Model
Anticipated Release Date: TBA The objective of this effort is to deliver a minimum viable predictive model prototype for PTSD …
Capabilities and Needs for Future Respiratory and Ocular Protection Systems
Anticipated Release Date: Q3FY25 This topic aims to provide novel, low-burden masks for the general purpose warfighter utilizing innovative materials …
Arctic Energy Seed Awards
Anticipated Release Date: TBA ConnectWerx, a Partnership Intermediary of DOE in collaboration with the Arctic Energy Office and the Office …
Vaccines Capability Area
Anticipated Release Date: Q3FY24 OR Q4FY24 Multiple Topics TBD—Possible 3 or 4 The goal of the Vaccines Capability Area is …
Accelerated Antibodies Modification
Anticipated Release Date: Q3FY24: Modification of existing Accelerated Antibodies agreement for additional monoclonal antibody prototype. Responding to this opportunity requires …
ChemDx Expansion
Anticipated Release Date: Q3FY24 Develop a diagnostic prototype strip, compatible with the ChemDx device, able to diagnose opioid exposure. Additional …
Development of Alternate Large Animal Models For Biothreats (Viral and Toxin) and Chemical Threats
Anticipated Release Date: Q4FY24 Development of alternate large animal models for biothreats (viral and toxin) and chemical threats. Due to …
Prototype MCMs to address the therapeutic indications of the Warfighter exposure to viral and bacterial biothreat agents
Anticipated Release Date: Q4FY24 The prioritizations on broad-spectrum direct-acting antivirals (nucleoside/nucleotide-like compounds and combination therapies) and host-directed broad-spectrum antivirals and …
Development of Novel, Broad Spectrum Countermeasures, and enabling capabilities for Toxin Exposure
Anticipated Release Date: Q4FY24 Prophylactic and therapeutic medical countermeasures for exposure to naturally occurring, synthetic and/or aerosolized toxins (excluding botulinum …
Mature Microphysiological System To Directly Compare To Well-Characterized Animal Model Results
Anticipated Release Date: Q4FY24 Develop a microphysiological system that realistically mimics human physiological responses to threat exposures for rapid discovery …
Therapeutics Capability Area
Anticipated Release Date: Q3FY24 OR Q4FY24 Multiple Topics TBD—Possible 3 or 4 The goal of the Therapeutics Capability Area is …
Shipboard Isolation System (SIS) / PPMT
Anticipated Release Date: Q4FY24 The SIS program provides the capability to temporarily isolate or quarantine personnel to prevent the spread …
Consolidated Nerve Agent Treatment System
Anticipated Release Date: Q1FY25 FDA approval of a multi-drug autoinjector to reduce logistical burden on the warfighter and increase survivability …
Agent Directed Therapeutic (ADTX) FY25 OTA
Anticipated Release Date: Q1FY25 New start OTA award for ADTX Responding to this opportunity requires membership in the Countering Weapons …
Autonomous Decontamination System (ADS) / PPMT
Anticipated Release Date: Q1FY25 The Autonomous Decontamination System program will provide a semi-autonomous supported capability that relies on precision detection …
VADER VaporAgent Demasking –Easily Readable
Anticipated Release Date: Q2FY25 VaporAgent Demasking –Easily Readable Develop low-burden, low-cost detection capabilities for chemical threat vapors to facilitate doffing …
Novelbioaerosol Detection and Identification Technologies
Anticipated Release Date: Q2FY25 Novel approaches to bioaerosol detection and identification that implement reliable, accurate and timely sampling mechanisms in a …
Diagnostic Platforms for Agnostictoxin Detections
Anticipated Release Date: Q2FY25 Develop diagnostic and detection assays, platforms, or devices to sense exposures of emerging toxins, to include …
Biocontainment Isolation System – Enhanced Biodefense (BCIS-ENBD)
Anticipated Release: Q3FY25 BCIS-ENBD will provide a ground-based isolation area for personnel infected or suspected of infection of biological organism …
Synthetic Binder Prediction, Synthesis, and Assay Development
Anticipated Release: Q3FY25 This effort will solicit multidisciplinary teams for a competition involving prediction of synthetic binders, synthesis of identified …
Capabilities and Needs for Future Respiratory and Ocular Protection Systems
Anticipated Release Date: Q3FY25 This topic aims to provide novel, low-burden masks for the general purpose warfighter utilizing innovative materials …
CIND, All States of Matters For Various Chemical Hazards
Anticipated Release: Q4FY25 Chemical indicators; Low-cost, easy to use, ultra-low SWaP modular open system based chemical detector that is widely …
Advanced System for Protection and Integrated Reduction of Encumbrances, ASPIRE
Anticipated Release Date: Q3FY26 ASPIRE will provide respiratory and ocular protection against Chemical, Biological, Radiological and Nuclear threats that allows …
Advanced Differential Diagnostics (ADD)
Anticipated Release: Q4FY27 Host response based test to predict illness severity. Responding to this opportunity requires membership in the Countering …
Active
MCDC: Broad Spectrum Prophylactics for Acetylcholinesterase Inhibitors
Due: October 8, 2025 The Joint Program Executive Office for Chemical, Biological, Radiological, and Nuclear Defense (JPEO-CBRND) focused on surveying …
Mathematical Biology
Due: October 14, 2025 The Mathematical Biology Program supports research in all areas of mathematical sciences with relevance to the …
Artificial Intelligence and Technology Collaboratory Coordinating Center
Due: October 15, 2025 This Notice of Funding Opportunity (NOFO) invites Cooperative Agreement (U24) applications for the National Institute on …
Windows on the Universe: The Era of Multi-Messenger Astrophysics
Due: October 15, 2025 The Universe is the ultimate laboratory, and we can now probe it as never before through …
DoD Toxic Exposures Translational Research Partnership Award
Due: October 16, 2025 The intent of the FY25 Toxic Exposures Research Program (TERP) Translational Research Partnership Award (TRPA) is …
DHA- Military Health System Research Program
Due: October 17, 2025 The Military Health System Research Program (MHSRP) provides research grants on topic areas directed by the …
Development of devices, diagnostic technologies, or digital health tools for treatment, detection, and diagnosis of Pediatric Cancers and/or Rare Cancers
Due: October 17, 2025 The goal of this solicitation is to encourage small businesses to propose “out of the box” …
Aging Mammalian Tissues In Vitro
Due: October 20, 2025 This notice of funding opportunity (NOFO) invites applications that propose interdisciplinary research that aims to develop …
Bidirectional Influences Between Adolescent Social Media Use and Mental Health
Due: October 20, 2025 This Notice of Funding Opportunity (NOFO) focuses on understanding bidirectional relationships between social media use and …
Clinical Trials Addressing Unmet Needs of Rare Neurodegenerative Diseases (R01) Clinical Trials Required
Due: October 21, 2025 The purpose of this Notice of Funding Opportunity (NOFO) is to fund clinical trials of products …
Geometric Analysis
Due: November 1, 2025 The program in Geometric Analysis supports research on differential geometry and its relation to partial differential …
Subsurface Void Detection Technologies
Due: November 3, 2025 Resource extraction companies require reliable data on all significant subsurface voids within the operational volume of …
CWX-024-CESER: Securing ENergy Technology ResiliencY (SENTRY)
Due: December 1, 2025 The U.S. Department of Energy (DOE), through its Office of Cybersecurity, Energy Security, and Emergency Response …
TechConnect Critical Technology Challenge: Advanced Materials
Due: December 15, 2025 The TechConnect Critical Technology Challenge: Advanced Materials is a premier open innovation program designed to accelerate solutions to …
TechConnect Critical Technology Challenge: Advanced Manufacturing
Due: December 15, 2025 The TechConnect Critical Technology Challenge: Advanced Manufacturing is a premier open innovation program designed to accelerate solutions to …
TechConnect Critical Technology Challenge: Artificial Intelligence
Due: December 15, 2025 The TechConnect Critical Technology Challenge: Artificial Intelligence is a premier open innovation program designed to accelerate solutions to …
TechConnect Critical Technology Challenge: Biotech and Medical
Due: December 15, 2025 The TechConnect Critical Technology Challenge: Biotech and Medical is a premier open innovation program designed to accelerate solutions …
TechConnect Critical Technology Challenge: Electronics and Microsystems
Due: December 15, 2025 The TechConnect Critical Technology Challenge: Electronics and Microsystems is a premier open innovation program designed to accelerate solutions …
TechConnect Critical Technology Challenge: Energy
Due: December 15, 2025 The TechConnect Critical Technology Challenge: Energy is a premier open innovation program designed to accelerate solutions to the …
TechConnect Critical Technology Challenge: Space, Defense and Mobility
Due: December 15, 2025 The TechConnect Critical Technology Challenge: Space, Defense and Mobility is a premier open innovation program designed to accelerate …
BioHealth Innovation Challenge
Due: January 22, 2026 Located in the heart of the Western United States, Las Vegas provides convenient access to nearby …
Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Natural Products
Due: July 14, 2026 This Notice of Funding Opportunity (NOFO) encourages cooperative agreement applications for investigator-initiated, multi-site, clinical trials (Phase …
Grant Opportunity: Research Projects to Enhance Applicability of Mammalian Models for Translational Research
DUE: September 7, 2026 The National Cancer Institute invites applications for projects to expand, improve, or transform the utility of …
Grant Opportunity: Assay development and screening for discovery of chemical probes, drugs or immunomodulators
DUE: September 7, 2026 Seeking applications for identification of small molecules that function to elucidate the biology of disease as …
Grant Opportunity: Personal Health Informatics for Delivering Actionable Insights to Individuals
DUE: November 5, 2026 Furthering the science of personal health informatics by providing meaningful and actionable insights to individuals through …
Grant Opportunity: Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics
DUE: January 7, 2027 Funding available to promote preclinical and patient based studies examining the mechanism(s) through which incretin mimetics …
Grant Opportunity: Improving Diagnostic Safety in Ambulatory Care
DUE: August 31, 2028 Funding opportunity to develop strategies and interventions to improve diagnostic safety in the heterogenous ambulatory care …
AHRQ Health Services Research Projects
Due: October 6, 2029 The purpose of this Notice of Funding Opportunity (NOFO) is to seek health services research grant …