Opportunities

NTA provides a curated pipeline of vetted opportunities aligned with industry and national priorities.  We are continuously consolidating new opportunities from Catalyst Partners, government requirements, and industry targets. Contact us to share your opportunities with NTA’s diverse community or organizations.  Join NTA today to receive email notifications.

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Modeling Criminal Case Processing Within Local Jurisdictions

Modeling Criminal Case Processing Within Local Jurisdictions

Anticipated Release Date: FY25 This opportunity does not require membership in America’s Datahub Consortium. However, if you win, you have …
Draft SOO: Operationalizing Novel Technologies for Advanced Rapid Generation of Effective MCMs

Draft SOO: Operationalizing Novel Technologies for Advanced Rapid Generation of Effective MCMs

Anticipated Release Date: Q4FY23 The Joint Science and Technology Office (JSTO) within the Defense Threat Reduction Agency (DTRA) is seeking …
Evaluating the Impact of State Grants on Self-Sufficiency for Families and Children

Evaluating the Impact of State Grants on Self-Sufficiency for Families and Children

Anticipated Release Date: FY25 The objective of this project is to link administrative data on housing participants with state block …
Providing Access to Updated, Aggregate Federal Workforce and Training Data to State, Local, and Territorial Governments

Providing Access to Updated, Aggregate Federal Workforce and Training Data to State, Local, and Territorial Governments

Anticipated Release Date: FY25 This project aims to develop a dashboard that provides up-to-date aggregate public federal workforce and training …
Sailor Post-Traumatic Stress Disorder (PTSD) Risk Prediction Model

Sailor Post-Traumatic Stress Disorder (PTSD) Risk Prediction Model

Anticipated Release Date: TBA The objective of this effort is to deliver a minimum viable predictive model prototype for PTSD …
Capabilities and Needs for Future Respiratory and Ocular Protection Systems

Capabilities and Needs for Future Respiratory and Ocular Protection Systems

Anticipated Release Date: Q3FY25 This topic aims to provide novel, low-burden masks for the general purpose warfighter utilizing innovative materials …
Arctic Energy Seed Awards

Arctic Energy Seed Awards

Anticipated Release Date: TBA ConnectWerx, a Partnership Intermediary of DOE in collaboration with the Arctic Energy Office and the Office …
Vaccines Capability Area

Vaccines Capability Area

Anticipated Release Date: Q3FY24 OR Q4FY24 Multiple Topics TBD—Possible 3 or 4 The goal of the Vaccines Capability Area is …
Accelerated Antibodies Modification

Accelerated Antibodies Modification

Anticipated Release Date: Q3FY24: Modification of existing Accelerated Antibodies agreement for additional monoclonal antibody prototype. Responding to this opportunity requires …
ChemDx Expansion

ChemDx Expansion

Anticipated Release Date: Q3FY24 Develop a diagnostic prototype strip, compatible with the ChemDx device, able to diagnose opioid exposure. Additional …
Development of Alternate Large Animal Models For Biothreats (Viral and Toxin) and Chemical Threats

Development of Alternate Large Animal Models For Biothreats (Viral and Toxin) and Chemical Threats

Anticipated Release Date: Q4FY24 Development of alternate large animal models for biothreats (viral and toxin) and chemical threats. Due to …
Prototype MCMs to address the therapeutic indications of the Warfighter exposure to viral and bacterial biothreat agents

Prototype MCMs to address the therapeutic indications of the Warfighter exposure to viral and bacterial biothreat agents

Anticipated Release Date: Q4FY24 The prioritizations on broad-spectrum direct-acting antivirals (nucleoside/nucleotide-like compounds and combination therapies) and host-directed broad-spectrum antivirals and …
Development of Novel, Broad Spectrum Countermeasures, and enabling capabilities for Toxin Exposure

Development of Novel, Broad Spectrum Countermeasures, and enabling capabilities for Toxin Exposure

Anticipated Release Date: Q4FY24 Prophylactic and therapeutic medical countermeasures for exposure to naturally occurring, synthetic and/or aerosolized toxins (excluding botulinum …
Mature Microphysiological System To Directly Compare To Well-Characterized Animal Model Results

Mature Microphysiological System To Directly Compare To Well-Characterized Animal Model Results

Anticipated Release Date: Q4FY24 Develop a microphysiological system that realistically mimics human physiological responses to threat exposures for rapid discovery …
Therapeutics Capability Area

Therapeutics Capability Area

Anticipated Release Date: Q3FY24 OR Q4FY24 Multiple Topics TBD—Possible 3 or 4 The goal of the Therapeutics Capability Area is …
Shipboard Isolation System (SIS) / PPMT

Shipboard Isolation System (SIS) / PPMT

Anticipated Release Date: Q4FY24 The SIS program provides the capability to temporarily isolate or quarantine personnel to prevent the spread …
IEW Phase 2 

IEW Phase 2 

Anticipated Release Date: Q4FY24 Establish Mission Planning and integration of the tactical, operational, Network convergence and CI/CD pipeline. This will allow …
Consolidated Nerve Agent Treatment System

Consolidated Nerve Agent Treatment System

Anticipated Release Date: Q1FY25 FDA approval of a multi-drug autoinjector to reduce logistical burden on the warfighter and increase survivability …
Agent Directed Therapeutic (ADTX) FY25 OTA

Agent Directed Therapeutic (ADTX) FY25 OTA

Anticipated Release Date: Q1FY25 New start OTA award for ADTX Responding to this opportunity requires membership in the Countering Weapons …
Autonomous Decontamination System (ADS) / PPMT 

Autonomous Decontamination System (ADS) / PPMT 

Anticipated Release Date: Q1FY25 The Autonomous Decontamination System program will provide a semi-autonomous supported capability that relies on precision detection …
VADER VaporAgent Demasking –Easily Readable

VADER VaporAgent Demasking –Easily Readable

Anticipated Release Date: Q2FY25 VaporAgent Demasking –Easily Readable Develop low-burden, low-cost detection capabilities for chemical threat vapors to facilitate doffing …
Novelbioaerosol Detection and Identification Technologies

Novelbioaerosol Detection and Identification Technologies

Anticipated Release Date: Q2FY25 Novel approaches to bioaerosol detection and identification that implement reliable, accurate and timely sampling mechanisms in a …
Diagnostic Platforms for Agnostictoxin Detections

Diagnostic Platforms for Agnostictoxin Detections

Anticipated Release Date: Q2FY25 Develop diagnostic and detection assays, platforms, or devices to sense exposures of emerging toxins, to include …
Biocontainment Isolation System - Enhanced Biodefense (BCIS-ENBD)

Biocontainment Isolation System – Enhanced Biodefense (BCIS-ENBD)

Anticipated Release: Q3FY25 BCIS-ENBD will provide a ground-based isolation area for personnel infected or suspected of infection of biological organism …
Synthetic Binder Prediction, Synthesis, and Assay Development

Synthetic Binder Prediction, Synthesis, and Assay Development

Anticipated Release: Q3FY25 This effort will solicit multidisciplinary teams for a competition involving prediction of synthetic binders, synthesis of identified …
Capabilities and Needs for Future Respiratory and Ocular Protection Systems

Capabilities and Needs for Future Respiratory and Ocular Protection Systems

Anticipated Release Date: Q3FY25 This topic aims to provide novel, low-burden masks for the general purpose warfighter utilizing innovative materials …
CIND, All States of Matters For Various Chemical Hazards

CIND, All States of Matters For Various Chemical Hazards

Anticipated Release: Q4FY25 Chemical indicators; Low-cost, easy to use, ultra-low SWaP modular open system based chemical detector that is widely …
Advanced System for Protection and Integrated Reduction of Encumbrances, ASPIRE

Advanced System for Protection and Integrated Reduction of Encumbrances, ASPIRE

Anticipated Release Date: Q3FY26 ASPIRE will provide respiratory and ocular protection against Chemical, Biological, Radiological and Nuclear threats that allows …
Advanced Differential Diagnostics (ADD)

Advanced Differential Diagnostics (ADD)

Anticipated Release: Q4FY27 Host response based test to predict illness severity. Responding to this opportunity requires membership in the Countering …

Active

TREXII: Modular VISMOD Program (MVP)

TREXII: Modular VISMOD Program (MVP)

Due: July 24, 2025 TREXII: Modular VISMOD Program (MVP) This opportunity requires membership in the TReXII Consortium. This Consortium releases …
Functional Validation and/or Characterization of Genes or Variants Implicated in Substance Use Disorders

Functional Validation and/or Characterization of Genes or Variants Implicated in Substance Use Disorders

Due: July 28, 2025 The purpose of this initiative is to support projects which exploit genome or epigenome editing to …
Countering Biological Weapons Threats

Countering Biological Weapons Threats

Due: July 30, 2025 ISN/CTR’s Biosecurity Engagement Program (BEP) advances the Trump Administration’s Executive Order (E.O.) on Improving the Safety …
NSTIC: Directed Energy Science & Engineering

NSTIC: Directed Energy Science & Engineering

Due: July 31, 2025 Directed Energy Science & Engineering This opportunity requires membership in the Naval Surface Technology and Innovation …
Perception, Action & Cognition

Perception, Action & Cognition

Due: August 1, 2025 The aim of the PAC program is to support empirically grounded, theoretically engaged and methodologically sophisticated …
Centers for AIDS Research

Centers for AIDS Research

Due: August 4, 2025 The purpose of this Funding Opportunity Announcement (FOA) is to invite applications for the Centers for …
Science of Learning and Augmented Intelligence (SL)

Science of Learning and Augmented Intelligence (SL)

Due: August 6, 2025 Science of Learning and Augmented Intelligence (SL) supports potentially transformative research that develops basic theoretical insights …
Quantum Characterization, Calibration, and Control (QC3)

Quantum Characterization, Calibration, and Control (QC3)

Due: August 7, 2025 DEVCOM Army Research Laboratory–Army Research Office (ARL-ARO) in partnership with the Laboratory for Physical Sciences (LPS) …
Seeking Solutions to Address Airflow and Contaminant Infiltration Across Dynamic Protective Interfaces (WRAITH)

Seeking Solutions to Address Airflow and Contaminant Infiltration Across Dynamic Protective Interfaces (WRAITH)

Due: August 8, 2025 The Joint Project Manager for Chemical, Biological, Radiological, and Nuclear Protection (JPM CBRN P) is conducting …
Grand Opportunity in Medications Development for Substance-Use Disorders

Grand Opportunity in Medications Development for Substance-Use Disorders

Due: August 11, 2025 The purpose of this notice of Funding Opportunity (NOFO) is to accelerate the development of medication …
ECosystem for Leading Innovation in Plasma Science and Engineering

ECosystem for Leading Innovation in Plasma Science and Engineering

Due: August 12, 2025 Plasma science is a transdisciplinary field of research where fundamental studies in many disciplines, including plasma …
Correctness for Scientific Computing Systems

Correctness for Scientific Computing Systems

Due: August 12, 2025 Correctness for Scientific Computing Systems (CS2) is a joint program of the National Science Foundation (NSF) …
Ex Vivo Models for Studies at the Intersection of HIV and Addictive Substance Use

Ex Vivo Models for Studies at the Intersection of HIV and Addictive Substance Use

Due: August 13, 2025 This Notice of Funding Opportunity (NOFO) invites grant applications aimed at elucidating neuroimmune and neuronal-glial pathophysiological …
Microglial Pathophysiology in Comorbid Substance Use Disorder (SUD) and HIV

Microglial Pathophysiology in Comorbid Substance Use Disorder (SUD) and HIV

Due: August 14, 2025 The goal of this funding opportunity announcement is to generate brain region and cell-type specific microglial …
Exploratory Studies to Investigate Mechanisms of HIV infection, Replication, Latency, and/or Pathogenesis in the Context of Substance Use Disorders

Exploratory Studies to Investigate Mechanisms of HIV infection, Replication, Latency, and/or Pathogenesis in the Context of Substance Use Disorders

Due: August 14, 2025 This broad RFA will support exploratory studies addressing mechanistic questions in HIV infection, replication, latency, and/or …
Cognitive Neuroscience

Cognitive Neuroscience

Due: August 15, 2025 The Cognitive Neuroscience (CogNeuro) program seeks to fund proposals that can advance our understanding of the …
Biological Oceanography

Biological Oceanography

Due: August 15, 2025 The Biological Oceanography Program supports fundamental research in biological oceanography and marine ecologyin environments ranging from …
Verticals-enabling Intelligent Network Systems

Verticals-enabling Intelligent Network Systems

Due: August 25, 2025 The VINES program seeks to support both fundamental research and verticals-driven technology development, demonstration, and translation …
DOD Amyotrophic Lateral Sclerosis, Therapeutic Idea Award

DOD Amyotrophic Lateral Sclerosis, Therapeutic Idea Award

Due: August 27, 2025 The fiscal year 2025 (FY25) Amyotrophic Lateral Sclerosis Research Program (ALSRP) Therapeutic Idea Award (TIA) supports …
Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Natural Products

Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Natural Products

Due: July 14, 2026 This Notice of Funding Opportunity (NOFO) encourages cooperative agreement applications for investigator-initiated, multi-site, clinical trials (Phase …
Grant Opportunity: Research Projects to Enhance Applicability of Mammalian Models for Translational Research

Grant Opportunity: Research Projects to Enhance Applicability of Mammalian Models for Translational Research

DUE: September 7, 2026 The National Cancer Institute invites applications for projects to expand, improve, or transform the utility of …
Grant Opportunity: Assay development and screening for discovery of chemical probes, drugs or immunomodulators

Grant Opportunity: Assay development and screening for discovery of chemical probes, drugs or immunomodulators

DUE: September 7, 2026 Seeking applications for identification of small molecules that function to elucidate the biology of disease as …
Grant Opportunity: Personal Health Informatics for Delivering Actionable Insights to Individuals

Grant Opportunity: Personal Health Informatics for Delivering Actionable Insights to Individuals

DUE: November 5, 2026 Furthering the science of personal health informatics by providing meaningful and actionable insights to individuals through …
Grant Opportunity: Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics

Grant Opportunity: Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics

DUE: January 7, 2027 Funding available to promote preclinical and patient based studies examining the mechanism(s) through which incretin mimetics …
Grant Opportunity: Improving Diagnostic Safety in Ambulatory Care

Grant Opportunity: Improving Diagnostic Safety in Ambulatory Care

DUE: August 31, 2028 Funding opportunity to develop strategies and interventions to improve diagnostic safety in the heterogenous ambulatory care …
AHRQ Health Services Research Projects

AHRQ Health Services Research Projects

Due: October 6, 2029 The purpose of this Notice of Funding Opportunity (NOFO) is to seek health services research grant …