NTA provides a curated pipeline of vetted opportunities aligned with industry and national priorities. We are continuously consolidating new opportunities from Catalyst Partners, government requirements, and industry targets. Contact us to share your opportunities with NTA’s diverse community or organizations. Join NTA today to receive email notifications.
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Draft SOO: Operationalizing Novel Technologies for Advanced Rapid Generation of Effective MCMs
Anticipated Release Date: Q4FY23 The Joint Science and Technology Office (JSTO) within the Defense Threat Reduction Agency (DTRA) is seeking …
Data Modernization: Future Directions for Data Collection Frames and Modeled Estimates
Anticipated Release Date: FY25 This project seeks to address the rapidly changing landscape of survey data collection and dissemination of …
Modeling Criminal Case Processing within Local Jurisdictions
Anticipated Release Date: FY25 The objective of this project is to explore the impact of criminal case processing from arrest …
Developing Fraud Risk Models in Support of Public Programs
Anticipated Release Date: FY25 The objective of this project is to develop new fraud detection methods to provide a more …
Evaluating the Impact of State Grants on Self-Sufficiency for Families and Children
Anticipated Release Date: FY25 The objective of this project is to link administrative data on housing participants with state block …
Providing Access to Updated, Aggregate Federal Workforce and Training Data to State, Local, and Territorial Governments
Anticipated Release Date: FY25 This project aims to develop a dashboard that provides up-to-date aggregate public federal workforce and training …
Data Usage Platform as a Federal Data Asset
Anticipated Release date: FY25 The key objective of this project is to develop an easy-to-maintain, user-friendly dashboard showing the utilization …
Technology Integration and Modernization of Expeditionary Medicine Warfighter Prototypes
Anticipated Release Date: TBA In order to modernize the DoD to be a ready and resilient Force, PMS 408 is …
Sailor Post-Traumatic Stress Disorder (PTSD) Risk Prediction Model
Anticipated Release Date: TBA The objective of this effort is to deliver a minimum viable predictive model prototype for PTSD …
Capabilities and Needs for Future Respiratory and Ocular Protection Systems
Anticipated Release Date: Q3FY25 This topic aims to provide novel, low-burden masks for the general purpose warfighter utilizing innovative materials …
Arctic Energy Seed Awards
Anticipated Release Date: TBA ConnectWerx, a Partnership Intermediary of DOE in collaboration with the Arctic Energy Office and the Office …
Vaccines Capability Area
Anticipated Release Date: Q3FY24 OR Q4FY24 Multiple Topics TBD—Possible 3 or 4 The goal of the Vaccines Capability Area is …
Accelerated Antibodies Modification
Anticipated Release Date: Q3FY24: Modification of existing Accelerated Antibodies agreement for additional monoclonal antibody prototype. Responding to this opportunity requires …
ChemDx Expansion
Anticipated Release Date: Q3FY24 Develop a diagnostic prototype strip, compatible with the ChemDx device, able to diagnose opioid exposure. Additional …
Development of Alternate Large Animal Models For Biothreats (Viral and Toxin) and Chemical Threats
Anticipated Release Date: Q4FY24 Development of alternate large animal models for biothreats (viral and toxin) and chemical threats. Due to …
Prototype MCMs to address the therapeutic indications of the Warfighter exposure to viral and bacterial biothreat agents
Anticipated Release Date: Q4FY24 The prioritizations on broad-spectrum direct-acting antivirals (nucleoside/nucleotide-like compounds and combination therapies) and host-directed broad-spectrum antivirals and …
Development of Novel, Broad Spectrum Countermeasures, and enabling capabilities for Toxin Exposure
Anticipated Release Date: Q4FY24 Prophylactic and therapeutic medical countermeasures for exposure to naturally occurring, synthetic and/or aerosolized toxins (excluding botulinum …
Mature Microphysiological System To Directly Compare To Well-Characterized Animal Model Results
Anticipated Release Date: Q4FY24 Develop a microphysiological system that realistically mimics human physiological responses to threat exposures for rapid discovery …
Therapeutics Capability Area
Anticipated Release Date: Q3FY24 OR Q4FY24 Multiple Topics TBD—Possible 3 or 4 The goal of the Therapeutics Capability Area is …
Shipboard Isolation System (SIS) / PPMT
Anticipated Release Date: Q4FY24 The SIS program provides the capability to temporarily isolate or quarantine personnel to prevent the spread …
IEW Phase 2
Anticipated Release Date: Q4FY24 Establish Mission Planning and integration of the tactical, operational, Network convergence and CI/CD pipeline. This will allow …
Consolidated Nerve Agent Treatment System
Anticipated Release Date: Q1FY25 FDA approval of a multi-drug autoinjector to reduce logistical burden on the warfighter and increase survivability …
Agent Directed Therapeutic (ADTX) FY25 OTA
Anticipated Release Date: Q1FY25 New start OTA award for ADTX Responding to this opportunity requires membership in the Countering Weapons …
Autonomous Decontamination System (ADS) / PPMT
Anticipated Release Date: Q1FY25 The Autonomous Decontamination System program will provide a semi-autonomous supported capability that relies on precision detection …
VADER VaporAgent Demasking –Easily Readable
Anticipated Release Date: Q2FY25 VaporAgent Demasking –Easily Readable Develop low-burden, low-cost detection capabilities for chemical threat vapors to facilitate doffing …
Novelbioaerosol Detection and Identification Technologies
Anticipated Release Date: Q2FY25 Novel approaches to bioaerosol detection and identification that implement reliable, accurate and timely sampling mechanisms in a …
Diagnostic Platforms for Agnostictoxin Detections
Anticipated Release Date: Q2FY25 Develop diagnostic and detection assays, platforms, or devices to sense exposures of emerging toxins, to include …
Shipboard Isolation System (SIS)
Anticipated Release Date: Q3FY25 SIS will provide the capability to temporarily isolate or quarantine personnel to prevent the spread of …
Biocontainment Isolation System – Enhanced Biodefense (BCIS-ENBD)
Anticipated Release: Q3FY25 BCIS-ENBD will provide a ground-based isolation area for personnel infected or suspected of infection of biological organism …
Synthetic Binder Prediction, Synthesis, and Assay Development
Anticipated Release: Q3FY25 This effort will solicit multidisciplinary teams for a competition involving prediction of synthetic binders, synthesis of identified …
Capabilities and Needs for Future Respiratory and Ocular Protection Systems
Anticipated Release Date: Q3FY25 This topic aims to provide novel, low-burden masks for the general purpose warfighter utilizing innovative materials …
CIND, All States of Matters For Various Chemical Hazards
Anticipated Release: Q4FY25 Chemical indicators; Low-cost, easy to use, ultra-low SWaP modular open system based chemical detector that is widely …
Advanced System for Protection and Integrated Reduction of Encumbrances, ASPIRE
Anticipated Release Date: Q3FY26 ASPIRE will provide respiratory and ocular protection against Chemical, Biological, Radiological and Nuclear threats that allows …
Advanced Differential Diagnostics (ADD)
Anticipated Release: Q4FY27 Host response based test to predict illness severity. Responding to this opportunity requires membership in the Countering …
Active
USGS Earthquake Hazards Program External Research Support Announcement for Fiscal Year 2026
Due: May 28, 2025 The USGS Earthquake Hazards Program (EHP) issues this annual Notice of Funding Opportunity (NOFO) for assistance …
Host-Directed Therapeutics
Due: May 30, 2025 The JPEO-CBRND is interested in late-stage development of host-directed therapeutics or repurposing of United States Food …
TechConnect Critical Technology Challenge: Operational Energy and Logistics
Due: May 30, 2025 Addressing Critical Technologies and National Priorities Submit your transformative operational energy, logistics, and cybersecurity of critical …
Immune Microphysiological Systems, IMPS
Due: May 31, 2025 JSTO is charged with addressing the potential threat to the armed services posed by a wide …
MSD Prevention Safety Innovation Challenge
Due: June 5, 2025 Through the MSD Prevention Safety Innovation Challenge, the National Safety Council is interested in innovative solutions …
Providing Customer Service for a National Secure Data Service Through a Data Concierge
Due: June 6, 2025 The key objective of this effort is to establish a centralized resource providing a broad set …
Industrialization and Translation of Extracellular Vesicles For Use In Regenerative Medicine
DUE: June 7, 2025 STTR Opportunity: Supporting the development of extracellular vesicle technologies for regenerative medical applications APPLY …
Reimagining Available Vaccines and Envisioning Novelty
Due: June 13, 2025 The Joint Science and Technology Office (JSTO) within the Defense Threat Reduction Agency (DTRA) supports the …
TechConnect Critical Technology Challenge: Space
Due: June 20, 2025 The TechConnect Critical Technology Challenge: Space is a premier open innovation program accelerating solutions to the most pressing …
TechConnect Critical Technology Challenge: Autonomy, AI, and Cyber
Due: June 20, 2025 The TechConnect Critical Technologies Challenge: Autonomy, AI, and Cyber is a premier open innovation program designed to accelerate …
TechConnect Critical Technology Challenge: Biotech and Health Security
Due: June 20, 2025 The TechConnect Critical Technologies Challenge: Biotech and Health Security is a premier open innovation program designed to accelerate …
TechConnect Critical Technology Challenge: Advanced Materials and Manufacturing
Due: June 20, 2025 The TechConnect Critical Technology Challenge: Advanced Materials and Manufacturing is a premier open innovation program designed to accelerate …
TechConnect Critical Technology Challenge: Energy and Resilience
Due: June 20, 2025 The TechConnect Critical Technology Challenge: Energy and Resilience is a premier open innovation program accelerating solutions for energy …
Industrialization and Translation of Extracellular Vesicles for use in Regenerative Medicine (U43/U44 Clinical Trials Not Allowed)
DUE: June 25, 2025 SBIR Opportunity: Supporting the development of extracellular vesicle technologies for regenerative medical applications. APPLY …
Collaborations Advancing Rapid Load Additions (CARLA)
Due: June 30, 2025 ConnectWerx, a Partnership Intermediary under a Partnership Intermediary Agreement (PIA) of the U.S. Department of Energy’s …
Cybersecurity Innovation for Cyberinfrastructure
Due: April 2, 2025 The objective of the Cybersecurity Innovation for Cyberinfrastructure (CICI) program is to advance scientific discovery and …
Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Natural Products
Due: July 14, 2026 This Notice of Funding Opportunity (NOFO) encourages cooperative agreement applications for investigator-initiated, multi-site, clinical trials (Phase …
Grant Opportunity: Research Projects to Enhance Applicability of Mammalian Models for Translational Research
DUE: September 7, 2026 The National Cancer Institute invites applications for projects to expand, improve, or transform the utility of …
Grant Opportunity: Assay development and screening for discovery of chemical probes, drugs or immunomodulators
DUE: September 7, 2026 Seeking applications for identification of small molecules that function to elucidate the biology of disease as …
Grant Opportunity: Personal Health Informatics for Delivering Actionable Insights to Individuals
DUE: November 5, 2026 Furthering the science of personal health informatics by providing meaningful and actionable insights to individuals through …
Grant Opportunity: Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics
DUE: January 7, 2027 Funding available to promote preclinical and patient based studies examining the mechanism(s) through which incretin mimetics …
Grant Opportunity: Improving Diagnostic Safety in Ambulatory Care
DUE: August 31, 2028 Funding opportunity to develop strategies and interventions to improve diagnostic safety in the heterogenous ambulatory care …
AHRQ Health Services Research Projects
Due: October 6, 2029 The purpose of this Notice of Funding Opportunity (NOFO) is to seek health services research grant …