Opportunities

NTA provides a curated pipeline of vetted opportunities aligned with industry and national priorities.  We are continuously consolidating new opportunities from Catalyst Partners, government requirements, and industry targets. Contact us to share your opportunities with NTA’s diverse community or organizations.  Join NTA today to receive email notifications.

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Upcoming

Modular AI/LLM Tools and Data Services for Integration with Digital OnRamp

Modular AI/LLM Tools and Data Services for Integration with Digital OnRamp

Anticipated Release Date: TBA The future of modular AI integration is here, and we’re seeking cutting-edge solutions to revolutionize how …
ConnectWerx: Solar Workforce Technical Assistance Program

ConnectWerx: Solar Workforce Technical Assistance Program

Anticipated Release Date: TBA ConnectWerx, a Partnership Intermediary of the U.S. Department of Energy (DOE) in collaboration with the Solar …
Arctic Energy Seed Awards

Arctic Energy Seed Awards

Anticipated Release Date: TBA ConnectWerx, a Partnership Intermediary of DOE in collaboration with the Arctic Energy Office and the Office …
Vaccines Capability Area

Vaccines Capability Area

Anticipated Release Date: Q3FY24 OR Q4FY24 Multiple Topics TBD—Possible 3 or 4 The goal of the Vaccines Capability Area is …
Accelerated Antibodies Modification

Accelerated Antibodies Modification

Anticipated Release Date: Q3FY24: Modification of existing Accelerated Antibodies agreement for additional monoclonal antibody prototype. Responding to this opportunity requires …
ChemDx Expansion

ChemDx Expansion

Anticipated Release Date: Q3FY24 Develop a diagnostic prototype strip, compatible with the ChemDx device, able to diagnose opioid exposure. Additional …
Development of Alternate Large Animal Models For Biothreats (Viral and Toxin) and Chemical Threats

Development of Alternate Large Animal Models For Biothreats (Viral and Toxin) and Chemical Threats

Anticipated Release Date: Q4FY24 Development of alternate large animal models for biothreats (viral and toxin) and chemical threats. Due to …
Prototype MCMs to address the therapeutic indications of the Warfighter exposure to viral and bacterial biothreat agents

Prototype MCMs to address the therapeutic indications of the Warfighter exposure to viral and bacterial biothreat agents

Anticipated Release Date: Q4FY24 The prioritizations on broad-spectrum direct-acting antivirals (nucleoside/nucleotide-like compounds and combination therapies) and host-directed broad-spectrum antivirals and …
Development of Novel, Broad Spectrum Countermeasures, and enabling capabilities for Toxin Exposure

Development of Novel, Broad Spectrum Countermeasures, and enabling capabilities for Toxin Exposure

Anticipated Release Date: Q4FY24 Prophylactic and therapeutic medical countermeasures for exposure to naturally occurring, synthetic and/or aerosolized toxins (excluding botulinum …
Mature Microphysiological System To Directly Compare To Well-Characterized Animal Model Results

Mature Microphysiological System To Directly Compare To Well-Characterized Animal Model Results

Anticipated Release Date: Q4FY24 Develop a microphysiological system that realistically mimics human physiological responses to threat exposures for rapid discovery …
Therapeutics Capability Area

Therapeutics Capability Area

Anticipated Release Date: Q3FY24 OR Q4FY24 Multiple Topics TBD—Possible 3 or 4 The goal of the Therapeutics Capability Area is …
Shipboard Isolation System (SIS) / PPMT

Shipboard Isolation System (SIS) / PPMT

Anticipated Release Date: Q4FY24 The SIS program provides the capability to temporarily isolate or quarantine personnel to prevent the spread …
Portable Patient Transport System -Enhanced Biodefense (PPTS-ENBD) / PPMT

Portable Patient Transport System -Enhanced Biodefense (PPTS-ENBD) / PPMT

Anticipated Release Date: Q4FY24 The Portable Patient Transport System Enhanced Biodefense (PPTS ENBD) is a patient transport system that enables …
IEW Phase 2 

IEW Phase 2 

Anticipated Release Date: Q4FY24 Establish Mission Planning and integration of the tactical, operational, Network convergence and CI/CD pipeline. This will allow …
Consolidated Nerve Agent Treatment System

Consolidated Nerve Agent Treatment System

Anticipated Release Date: Q1FY25 FDA approval of a multi-drug autoinjector to reduce logistical burden on the warfighter and increase survivability …
Agent Directed Therapeutic (ADTX) FY25 OTA

Agent Directed Therapeutic (ADTX) FY25 OTA

Anticipated Release Date: Q1FY25 New start OTA award for ADTX Responding to this opportunity requires membership in the Countering Weapons …
Autonomous Decontamination System (ADS) / PPMT 

Autonomous Decontamination System (ADS) / PPMT 

Anticipated Release Date: Q1FY25 The Autonomous Decontamination System program will provide a semi-autonomous supported capability that relies on precision detection …
VADER VaporAgent Demasking –Easily Readable

VADER VaporAgent Demasking –Easily Readable

Anticipated Release Date: Q2FY25 VaporAgent Demasking –Easily Readable Develop low-burden, low-cost detection capabilities for chemical threat vapors to facilitate doffing …
Novelbioaerosol Detection and Identification Technologies

Novelbioaerosol Detection and Identification Technologies

Anticipated Release Date: Q2FY25 Novel approaches to bioaerosol detection and identification that implement reliable, accurate and timely sampling mechanisms in a …
Diagnostic Platforms for Agnostictoxin Detections

Diagnostic Platforms for Agnostictoxin Detections

Anticipated Release Date: Q2FY25 Develop diagnostic and detection assays, platforms, or devices to sense exposures of emerging toxins, to include …
Portable Patient Transport System – Enhanced Biodefense, PPTS-ENBD

Portable Patient Transport System – Enhanced Biodefense, PPTS-ENBD

Anticipated Release Date: Q3FY25 PPTS-ENBD will provide a biocontainment isolation system to safely transport personnel infected or suspected of infection …
Shipboard Isolation System (SIS)

Shipboard Isolation System (SIS)

Anticipated Release Date: Q3FY25 SIS will provide the capability to temporarily isolate or quarantine personnel to prevent the spread of …
Biocontainment Isolation System - Enhanced Biodefense (BCIS-ENBD)

Biocontainment Isolation System – Enhanced Biodefense (BCIS-ENBD)

Anticipated Release: Q3FY25 BCIS-ENBD will provide a ground-based isolation area for personnel infected or suspected of infection of biological organism …
Synthetic Binder Prediction, Synthesis, and Assay Development

Synthetic Binder Prediction, Synthesis, and Assay Development

Anticipated Release: Q3FY25 This effort will solicit multidisciplinary teams for a competition involving prediction of synthetic binders, synthesis of identified …
Capabilities and Needs for Future Respiratory and Ocular Protection Systems

Capabilities and Needs for Future Respiratory and Ocular Protection Systems

Anticipated Release Date: Q3FY25 This topic aims to provide novel, low-burden masks for the general purpose warfighter utilizing innovative materials …
CIND, All States of Matters For Various Chemical Hazards

CIND, All States of Matters For Various Chemical Hazards

Anticipated Release: Q4FY25 Chemical indicators; Low-cost, easy to use, ultra-low SWaP modular open system based chemical detector that is widely …
CBRN Sensor Integration On Robotic Platforms (CSIRP) Capability Set (CS) 4.0

CBRN Sensor Integration On Robotic Platforms (CSIRP) Capability Set (CS) 4.0

Anticipated Release: Q4FY25 The Government is seeking proposals for development and integration of new CBRN sensing payloads, using common interfaces, …
Far Forward Biological Sequencing (FFBS), Increment 2

Far Forward Biological Sequencing (FFBS), Increment 2

Anticipated Release: Q1FY26 FFBS Increment 2 will focus on automating the sample preparation process and meeting any key performance parameter …
Advanced System for Protection and Integrated Reduction of Encumbrances, ASPIRE

Advanced System for Protection and Integrated Reduction of Encumbrances, ASPIRE

Anticipated Release Date: Q3FY26 ASPIRE will provide respiratory and ocular protection against Chemical, Biological, Radiological and Nuclear threats that allows …
Advanced Differential Diagnostics (ADD)

Advanced Differential Diagnostics (ADD)

Anticipated Release: Q4FY27 Host response based test to predict illness severity. Responding to this opportunity requires membership in the Countering …

Active

Orbital Edge Accelerator

Orbital Edge Accelerator

Due: May 19, 2025 We live in a golden era of space industry innovation and growth that creates amazing opportunities …
SOFWERX: Down Range Crosswind Sensing (DR-CWS)

SOFWERX: Down Range Crosswind Sensing (DR-CWS)

Due: May 21, 2025 The objective of this topic is to develop applied research towards developing the capability to measure …
TREXII Red Giant

TREXII Red Giant

Due: May 27, 2025 The Test Resource Management Center (TRMC) is looking for information related to classified technology development. In …
TechConnect Critical Technology Challenge: Operational Energy and Logistics

TechConnect Critical Technology Challenge: Operational Energy and Logistics

Due: May 30, 2025 Addressing Critical Technologies and National Priorities Submit your transformative operational energy, logistics, and cybersecurity of critical …
Immune Microphysiological Systems, IMPS

Immune Microphysiological Systems, IMPS

Due: May 31, 2025 JSTO is charged with addressing the potential threat to the armed services posed by a wide …
MSD Prevention Safety Innovation Challenge

MSD Prevention Safety Innovation Challenge

Due: June 5, 2025 Through the MSD Prevention Safety Innovation Challenge, the National Safety Council is interested in innovative solutions …
Industrialization and Translation of Extracellular Vesicles For Use In Regenerative Medicine

Industrialization and Translation of Extracellular Vesicles For Use In Regenerative Medicine

DUE: June 7, 2025 STTR Opportunity: Supporting the development of extracellular vesicle technologies for regenerative medical applications APPLY …
TechConnect Critical Technology Challenge: Space

TechConnect Critical Technology Challenge: Space

Due: June 20, 2025 The TechConnect Critical Technology Challenge: Space is a premier open innovation program accelerating solutions to the most pressing …
TechConnect Critical Technology Challenge: Autonomy, AI, and Cyber

TechConnect Critical Technology Challenge: Autonomy, AI, and Cyber

Due: June 20, 2025 The TechConnect Critical Technologies Challenge: Autonomy, AI, and Cyber is a premier open innovation program designed to accelerate …
TechConnect Critical Technology Challenge: Biotech and Health Security

TechConnect Critical Technology Challenge: Biotech and Health Security

Due: June 20, 2025 The TechConnect Critical Technologies Challenge: Biotech and Health Security is a premier open innovation program designed to accelerate …
TechConnect Critical Technology Challenge: Advanced Materials and Manufacturing

TechConnect Critical Technology Challenge: Advanced Materials and Manufacturing

Due: June 20, 2025 The TechConnect Critical Technology Challenge: Advanced Materials and Manufacturing is a premier open innovation program designed to accelerate …
TechConnect Critical Technology Challenge: Energy and Resilience

TechConnect Critical Technology Challenge: Energy and Resilience

Due: June 20, 2025 The TechConnect Critical Technology Challenge: Energy and Resilience is a premier open innovation program accelerating solutions for energy …
Industrialization and Translation of Extracellular Vesicles for use in Regenerative Medicine (U43/U44 Clinical Trials Not Allowed)

Industrialization and Translation of Extracellular Vesicles for use in Regenerative Medicine (U43/U44 Clinical Trials Not Allowed)

DUE: June 25, 2025 SBIR Opportunity: Supporting the development of extracellular vesicle technologies for regenerative medical applications. APPLY …
Collaborations Advancing Rapid Load Additions (CARLA)

Collaborations Advancing Rapid Load Additions (CARLA)

Due: TBA ConnectWerx, a Partnership Intermediary under a  Partnership Intermediary Agreement (PIA) of the U.S. Department of Energy’s (DOE) Grid …
Cybersecurity Innovation for Cyberinfrastructure

Cybersecurity Innovation for Cyberinfrastructure

Due: April 2, 2025 The objective of the Cybersecurity Innovation for Cyberinfrastructure (CICI) program is to advance scientific discovery and …
Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Natural Products

Clinical Coordinating Center for NCCIH Multi-Site Investigator-Initiated Clinical Trials of Natural Products

Due: July 14, 2026 This Notice of Funding Opportunity (NOFO) encourages cooperative agreement applications for investigator-initiated, multi-site, clinical trials (Phase …
Grant Opportunity: Research Projects to Enhance Applicability of Mammalian Models for Translational Research

Grant Opportunity: Research Projects to Enhance Applicability of Mammalian Models for Translational Research

DUE: September 7, 2026 The National Cancer Institute invites applications for projects to expand, improve, or transform the utility of …
Grant Opportunity: Assay development and screening for discovery of chemical probes, drugs or immunomodulators

Grant Opportunity: Assay development and screening for discovery of chemical probes, drugs or immunomodulators

DUE: September 7, 2026 Seeking applications for identification of small molecules that function to elucidate the biology of disease as …
Grant Opportunity: Personal Health Informatics for Delivering Actionable Insights to Individuals

Grant Opportunity: Personal Health Informatics for Delivering Actionable Insights to Individuals

DUE: November 5, 2026 Furthering the science of personal health informatics by providing meaningful and actionable insights to individuals through …
Grant Opportunity: Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics

Grant Opportunity: Mechanisms that Impact Cancer Risk with Use of Incretin Mimetics

DUE: January 7, 2027 Funding available to promote preclinical and patient based studies examining the mechanism(s) through which incretin mimetics …
Grant Opportunity: Improving Diagnostic Safety in Ambulatory Care

Grant Opportunity: Improving Diagnostic Safety in Ambulatory Care

DUE: August 31, 2028 Funding opportunity to develop strategies and interventions to improve diagnostic safety in the heterogenous ambulatory care …
AHRQ Health Services Research Projects

AHRQ Health Services Research Projects

Due: October 6, 2029 The purpose of this Notice of Funding Opportunity (NOFO) is to seek health services research grant …